The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2014
Filed:
Aug. 18, 2009
Ib Jonassen, Valby, DK;
Michi Egel-mitani, Vedbaek, DK;
Per Balschmidt, Espergaerde, DK;
Jan Markussen, Herlev, DK;
Ivan Diers, Vaerlose, DK;
Thomas Borglum Kjeldsen, Virum, DK;
Ib Jonassen, Valby, DK;
Michi Egel-Mitani, Vedbaek, DK;
Per Balschmidt, Espergaerde, DK;
Jan Markussen, Herlev, DK;
Ivan Diers, Vaerlose, DK;
Thomas Borglum Kjeldsen, Virum, DK;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The present invention related to a method of producing polypeptides in transformed host cells by expressing a precursor molecule of the desired polypeptide which are to be acylated in a subsequent in vitro step. The invention is also related to DNA-sequences, vectors and transformed host cells for use in the claimed method. Further, the present invention is related to certain precursors of the desired polypeptides and certain acylation methods. The invention provides a method for making polypeptides being preferentially acylated in certain lysine ε-amino groups.