The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2014

Filed:

Dec. 16, 2011
Applicants:

Robert G. Kuimelis, Palo Alto, CA (US);

Glenn H. Mcgall, Palo Alto, CA (US);

Stephen P. A. Fodor, Palo Alto, CA (US);

Inventors:

Robert G. Kuimelis, Palo Alto, CA (US);

Glenn H. McGall, Palo Alto, CA (US);

Stephen P. A. Fodor, Palo Alto, CA (US);

Assignee:

Affymetrix, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/00 (2006.01); G01N 33/00 (2006.01); G01N 33/53 (2006.01); C12Q 1/00 (2006.01); C12N 9/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compositions and methods for the labeling of two or more targets with different labels. Specifically, disclosed are compositions for biotin and the protection of biotin within multilabel assays which employ the biotin-biotin binding protein binding relationship for each distinct label in relation to targets such as nucleic acids, polypeptides, antibodies or cells. These multilabel assays are enabled through the use of biotin with desthiobiotin, orthogonal protecting schemes for biotin, or a combination of the approaches.


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