The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8834794 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 16, 2014

Filed:

Nov. 22, 2011
Applicants:

Mehdi M Yazdanpanah, Louisville, KY (US);

Romaneh Jalilian, Lousiville, KY (US);

Inventors:

Mehdi M Yazdanpanah, Louisville, KY (US);

Romaneh Jalilian, Lousiville, KY (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/00 (2006.01); C12M 3/06 (2006.01); G01N 33/50 (2006.01); B01L 3/00 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); B01L 2400/086 (2013.01); B01L 2300/0816 (2013.01); G01N 33/5094 (2013.01); B01L 2300/0645 (2013.01); B01L 2200/0668 (2013.01); B01L 3/502761 (2013.01); C12M 41/36 (2013.01); B01L 2300/0883 (2013.01);
Abstract

In one embodiment, the present invention provides the description of an inexpensive and disposable handheld device for detecting Circulating tumor cells (CTC) in blood called a handheld CTC detector (HCTCD). The HCTCD is capable of detecting less than 1 CTC per milliliter. The HCTCD consists of a dense array of high aspect ratio freestanding metallic nanoneedles, functionalized with antibodies that integrated within a microfluidic device and selectively capture and count (using electrical signal detection) the CTCs. By selecting a right functionalization protocol for the nanoneedles array, the HCTCD can be used for selective capturing a variety of rare cells that are mixed in human fluids.


Find Patent Forward Citations

Yazdanpanah, Mehdi. (2014). Apparatus and methods for detection of tumor cells in blood (U.S. Patent No. 8834794). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8834794

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