The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Dec. 21, 2006
Applicants:
Stefan Barth, Aachen, DE;
Ulrich Wüllner, Bielefeld, DE;
Inga Neef, Stolberg, DE;
Inventors:
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C12N 2310/14 (2013.01); C12N 15/111 (2013.01); C12N 2310/351 (2013.01); C12N 15/1135 (2013.01); C12N 2310/3519 (2013.01); C12N 15/113 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01); C12N 2310/16 (2013.01); C12N 2310/11 (2013.01);
Abstract
Subject of the invention is a compound, consisting of a targeting moiety which specifically binds to a disease related cell surface marker, a nucleic acid which specifically induces cell death and a linker, wherein the linker covalently links the targeting moiety to the nucleic acid. Subject of the invention are also medicaments comprising the compound and their use as a medicament for the treatment of diseases, including proliferative diseases.