The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Oct. 20, 2009
Applicants:
Kevin Thorne, Austin, TX (US);
Rama Akella, Austin, TX (US);
Inventors:
Kevin Thorne, Austin, TX (US);
Rama Akella, Austin, TX (US);
Assignee:
Zimmer Orthobiologics, Inc., Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/51 (2006.01); C07K 14/145 (2006.01); C07K 1/14 (2006.01); C07K 1/34 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for purifying bone-derived osteoinductive proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular weight ultrafiltration process, and a recover process. The high and low ultrafiltration processes preferably select proteins having a nominal molecular weight between approximately 8 kilodaltons and approximately 100 kilodaltons. Processes of the present invention may be used to recover osteoinductive proteins from bone demineralization waste streams.