The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
May. 24, 2005
Applicants:
Geoffrey C. Gurtner, New York, NY (US);
Michael A. Brownlee, New York, NY (US);
Inventors:
Geoffrey C. Gurtner, New York, NY (US);
Michael A. Brownlee, New York, NY (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/13 (2006.01); A61K 31/19 (2006.01); A61K 31/385 (2006.01); A61K 31/555 (2006.01); A61K 31/198 (2006.01);
U.S. Cl.
CPC ...
A61K 31/385 (2013.01); A61K 31/555 (2013.01); A61K 31/198 (2013.01);
Abstract
One aspect of the present invention relates to a method of treating or preventing pathologic sequelae of acute hyperglycemia and/or increased fatty acid flux in a subject. This method involves administering an ROS inhibitor to the subject. In addition, methods of promoting neovascularization, inhibiting oxidation or excessive release of free fatty acids, and identifying compounds suitable for treatment or prevention of ROS-mediated injury are also disclosed.