The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Oct. 22, 2009
Applicants:

Matthias Eckhardt, Biberach an der Riss, DE;

Bradford S. Hamilton, Biberach an der Riss, DE;

Frank Himmelsbach, Mittelbiberach, DE;

Inventors:

Matthias Eckhardt, Biberach an der Riss, DE;

Bradford S. Hamilton, Biberach an der Riss, DE;

Frank Himmelsbach, Mittelbiberach, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/46 (2006.01); C07D 451/02 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 451/02 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to compounds defined by formula I wherein the groups R, Yto Y, V, W, and X are defined as in claim, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11 β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases, in particular diabetes type 2, obesity, and dyslipidemia.


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