The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Feb. 10, 2012
Applicants:
Xavier Berzosa Rodríguez, L'Hospitalet del Llobregat, ES;
Francisco Marquillas Olondriz, Barcelona, ES;
Inventors:
Xavier Berzosa Rodríguez, L'Hospitalet del Llobregat, ES;
Francisco Marquillas Olondriz, Barcelona, ES;
Assignee:
Interquim, S.A., Sant Cugat del Vallès, ES;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/42 (2006.01); A61K 31/44 (2006.01); C07D 221/18 (2006.01); C07D 471/00 (2006.01); C07D 498/00 (2006.01); C07D 515/00 (2006.01); C07D 221/22 (2006.01); C07D 221/06 (2006.01); C07D 491/00 (2006.01); C07D 471/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 471/04 (2013.01);
Abstract
The invention relates to a process for obtaining compounds derived from tetrahydro-β-carboline, specifically tadalafil and intermediate products from the synthesis, comprising the reaction between piperonal and an alkyl ester of D-tryptophan as a salt, and in the absence of any other component, followed by haloacetylation and a final cyclization with methylamine.