The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Oct. 23, 2009
Applicants:

Kotoe Ohta, Kamakura, JP;

Suguru Takaki, Kamakura, JP;

Yasuhide Horiuchi, Kamakura, JP;

Inventors:

Kotoe Ohta, Kamakura, JP;

Suguru Takaki, Kamakura, JP;

Yasuhide Horiuchi, Kamakura, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 31/485 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2059 (2013.01); A61K 9/2009 (2013.01); A61K 9/2018 (2013.01); A61K 31/485 (2013.01); A61K 9/1623 (2013.01); A61K 9/1676 (2013.01); A61K 9/2027 (2013.01);
Abstract

The present invention relates to a stable tablet comprising a 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt thereof as an effective ingredient. That is, the tablet according to the present invention comprises: (1) as the effective ingredient, a specific 4,5-epoxymorphinan derivative or a pharmacologically acceptable acid addition salt; (2) sodium thiosulfate; (3) at least one selected from the group consisting of saccharides and sugar alcohols; and (4) crospovidone, sodium carboxymethyl starch or a mixture thereof, in which tablet the content of the aforementioned (4) is 1 to 20% by weight per unit weight containing the aforementioned effective ingredient.


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