The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Sep. 28, 2009
Applicants:

Jin LI, Beijing, CN;

Rifang Yang, Beijing, CN;

Rui Song, Beijing, CN;

Hui Zhu, Beijing, CN;

Ning Wu, Beijing, CN;

Liuhong Yun, Beijing, CN;

Ruibin Su, Beijing, CN;

Rusheng Zhao, Beijing, CN;

Inventors:

Jin Li, Beijing, CN;

Rifang Yang, Beijing, CN;

Rui Song, Beijing, CN;

Hui Zhu, Beijing, CN;

Ning Wu, Beijing, CN;

Liuhong Yun, Beijing, CN;

Ruibin Su, Beijing, CN;

Rusheng Zhao, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/506 (2006.01); C07D 263/58 (2006.01); C07D 277/68 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); C07D 277/68 (2013.01); C07D 263/58 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention relates to a novel piperazine derivative represented by Formula I having an activity for regulating dopamine D3 receptor, stereoisomers thereof, pharmaceutically acceptable salts or solvates, and a pharmaceutical composition comprising the compound, a process for preparing the same, and use thereof in the prevention or treatment of a disease associated with central nervous system dysfunction, such as Parkinson's disease, schizophrenia, drug addiction and relapse, as well as kidney protection and immunoregulation, or as a tool for researching D3R function or diseases associated with D3R dysfunction.


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