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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8828992 B1

PDFFull Text
Date of Patent:
Sep. 09, 2014

Filed:

Feb. 25, 2010

Substituted azole derivatives, pharmaceutical composition containing the derivatives, and method for treating parkinson's disease using the same

Applicants:

Cheol-hyoung Park, Daejeon, KR;

Hye-kyung Min, Daejeon, KR;

Mi-jung Lim, Daejeon, KR;

Ji-won Lee, Daejeon, KR;

Jin-yong Chung, Daejeon, KR;

Choon-ho Ryu, Daejeon, KR;

Yeo-jin Yoon, Daejeon, KR;

Mi-kyung Ji, Seoul, KR;

Joo-young Park, Daejeon, KR;

Inventors:

Cheol-Hyoung Park, Daejeon, KR;

Hye-Kyung Min, Daejeon, KR;

Mi-Jung Lim, Daejeon, KR;

Ji-Won Lee, Daejeon, KR;

Jin-Yong Chung, Daejeon, KR;

Choon-Ho Ryu, Daejeon, KR;

Yeo-Jin Yoon, Daejeon, KR;

Mi-Kyung Ji, Seoul, KR;

Joo-Young Park, Daejeon, KR;

Assignee:

SK Biopharmaceuticals Co., Ltd., Seoul, KR;

Attorney:

Harness, Dickey & Pierce, P.L.C.

Primary Examiner:

Nobel Jarrell

Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 31/5377 (2006.01); A61K 31/4439 (2006.01); A61K 31/42 (2006.01); C07D 413/06 (2006.01); C07D 413/12 (2006.01); C07D 261/08 (2006.01); C07D 263/32 (2006.01); C07D 277/02 (2006.01); A61K 45/06 (2006.01); C07D 249/10 (2006.01); A61K 31/554 (2006.01); A61K 31/16 (2006.01); A61K 31/198 (2006.01);
U.S. Cl.
CPC ...
C07D 277/02 (2013.01); A61K 45/06 (2013.01); C07D 249/10 (2013.01); A61K 31/554 (2013.01); A61K 31/16 (2013.01); A61K 31/198 (2013.01);
Abstract

Provided are a substituted azole derivative and pharmaceutically acceptable salts thereof, a pharmaceutical composition including an effective amount of the derivative, and a method for treating Parkinson's disease in a mammal including administering an effective amount of the compound to the mammal. The azole derivative of the following Formula (I) and pharmaceutically useful salts thereof have an efficacy against Parkinson's disease from inhibitory effects of the activity of MAO-B.

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