The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Apr. 24, 2012
Applicants:

Yong MI Choi-sledeski, Belle Mead, NJ (US);

Julian Levell, Arlington, MA (US);

Gregory Bernard Poli, Bethlehem, PA (US);

Mark Czekaj, Doylestown, PA (US);

Alan John Collis, Lexington, MA (US);

Roy Vaz, Branchburg, NJ (US);

Inventors:

Yong Mi Choi-Sledeski, Belle Mead, NJ (US);

Julian Levell, Arlington, MA (US);

Gregory Bernard Poli, Bethlehem, PA (US);

Mark Czekaj, Doylestown, PA (US);

Alan John Collis, Lexington, MA (US);

Roy Vaz, Branchburg, NJ (US);

Assignee:

Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 57/00 (2006.01); A61K 31/675 (2006.01); C07C 229/00 (2006.01); C07F 9/28 (2006.01); C07F 9/06 (2006.01); C07F 9/02 (2006.01); C07F 9/547 (2006.01); C07F 9/6506 (2006.01); C07K 5/08 (2006.01); C07F 9/30 (2006.01); C07K 5/06 (2006.01); C07F 9/6503 (2006.01); C07F 9/572 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/0827 (2013.01); C07F 9/65067 (2013.01); A61K 38/00 (2013.01); C07F 9/303 (2013.01); C07F 9/301 (2013.01); C07K 5/06191 (2013.01); C07F 9/65037 (2013.01); C07F 9/5728 (2013.01); C07F 9/5727 (2013.01);
Abstract

The present invention relates to a series of substituted 3-aminopropane phosphinic acid derivatives of formula I: wherein R, R, P, Pand Pare as defined herein. The compounds of this invention are useful in treating a variety of diseases including but not limited to depression, anxiety, certain psychiatric symptoms, cognitive impairment and schizophrenia.


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