The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Mar. 11, 2010
Applicants:

Petra Seemann, Berlin, DE;

Stefan Mundlos, Kleinmachnow, DE;

Carsten Reissner, Muenster, DE;

Georg Duda, Berlin, DE;

Julia Zimmer, Berlin, DE;

Inventors:

Petra Seemann, Berlin, DE;

Stefan Mundlos, Kleinmachnow, DE;

Carsten Reissner, Muenster, DE;

Georg Duda, Berlin, DE;

Julia Zimmer, Berlin, DE;

Assignee:

Haase Investments UG, Alfeld (Leine), DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/435 (2006.01); C07K 14/46 (2006.01); C07K 14/465 (2006.01); C07K 14/51 (2006.01); C12N 15/00 (2006.01); C12N 15/12 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to an isolated peptide comprising or consisting of an amino acid sequence with an amino acid identity of at least 90% compared to mature human BMP2 with SEQ ID No. 1, characterized in that said amino acid sequence comprises at least two amino acid substitutions characterized in that a first amino acid substitution occurs at a position corresponding to N59, S88, E94, V99, K101 and/or N102 of SEQ ID No. 1 and to uses thereof.


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