The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Feb. 11, 2011
Robert C. Axtell, Menlo Park, CA (US);
Lawrence Steinman, Stanford, CA (US);
May H. Han, Menlo Park, CA (US);
Brigit A. DE Jong, Nijmegen, NL;
Chander Raman, Birmingham, AL (US);
Michael Walker, Carlsbad, CA (US);
Jing Shi, Carlsbad, CA (US);
Robert C. Axtell, Menlo Park, CA (US);
Lawrence Steinman, Stanford, CA (US);
May H. Han, Menlo Park, CA (US);
Brigit A. de Jong, Nijmegen, NL;
Chander Raman, Birmingham, AL (US);
Michael Walker, Carlsbad, CA (US);
Jing Shi, Carlsbad, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Abstract
Compositions and methods are provided for prognostic classification of inflammatory diseases, e.g. inflammatory demyelinating disease, patients into subtypes, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest. The patterns of cytokines provides for a signature pattern that can identify patients likely to benefit from therapeutic intervention as well as discriminate patients that have a high probability of responsiveness to a therapy from those that have a low probability of responsiveness. Assessment of this signature pattern thus allows improved methods of care. In one embodiment of the invention, the autoimmune disease is multiple sclerosis or neuromyelitis optica.