The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Jul. 05, 2010
Applicants:
Paul Britton, Hungerford, GB;
Erica Bickerton, Oxford, GB;
Maria Armesto, San Sebastian, ES;
Inventors:
Assignee:
The Pirbright Institute, Pirbright, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); C12N 7/01 (2006.01); C12N 7/02 (2006.01); C12N 5/10 (2006.01); C12N 15/50 (2006.01); C07K 19/00 (2006.01); C07K 14/165 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a chimaeric coronavirus S protein which is based on an S protein from a coronavirus strain with restricted tissue tropism, but which comprises at least part of the S2 subunit from a coronavirus strain with extended tissue tropism, such that a virus comprising the chimaeric S protein has extended tissue tropism. The present invention also provides a virus comprising such a chimaeric S protein.