The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
May. 15, 2012
Louis Denis, Wiesbaden, DE;
Robert Michael Lorence, Bethesda, MD (US);
Mehdi Shahidi, Sutton, GB;
Flavio Solca, Vienna, AT;
Louis Denis, Wiesbaden, DE;
Robert Michael Lorence, Bethesda, MD (US);
Mehdi Shahidi, Sutton, GB;
Flavio Solca, Vienna, AT;
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
The present invention relates to a method of treating patients suffering from cancers driven by deregulated Human Epidermal Growth Factor Receptor (HER/Human EGFR), wherein an irreversible tyrosine kinase inhibitor (TKI) is administered according to a continuous regimen based on an average daily dose in the range of 10 to 50 mg and the mAB is co-administered according to a dosing regimen ranging from an average weekly iv dose of 50 to 500 mg/mrepeated thrice, twice or once a week, once in two weeks, once in three weeks or at least monthly to a patient in need of such treatment.