The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2014
Filed:
Jul. 07, 2010
Masunori Kajikawa, Komagane, JP;
Masahito Sugiura, Komagane, JP;
Kazuyuki Atarashi, Komagane, JP;
Emi Shimizu, Komagane, JP;
Chiemi Matsumi, Komagane, JP;
Yukie Saitoh, Komagane, JP;
Masunori Kajikawa, Komagane, JP;
Masahito Sugiura, Komagane, JP;
Kazuyuki Atarashi, Komagane, JP;
Emi Shimizu, Komagane, JP;
Chiemi Matsumi, Komagane, JP;
Yukie Saitoh, Komagane, JP;
Actgen Inc, Nagano, JP;
Abstract
By utilizing an SST-REX method, a cDNA encoding a protein expressed on a cell surface or secreted from the cell was selected from a cDNA library derived from a cancer cell line. Monoclonal antibodies against the protein encoding the selected cDNA were prepared. The in vitro and in vivo anti-cancer activities and binding to various cancer cells lines were examined. As a result, a monoclonal antibody which binds to a PODXL2 protein, and which had excellent anti-cancer activities was found. Further, a region including an epitope of the antibody was successfully identified, and the amino acid sequences of variable regions of a light chain and a heavy chain were successfully determined.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile