The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2014

Filed:

Jul. 26, 2013
Applicant:

Sigma-tau Industrie Farmaceutiche Riunite S.p.a., Rome, IT;

Inventors:

Alberto Cerri, Milan, IT;

Mauro Gobbini, Mercallo, IT;

Marco Torri, Rho, IT;

Patrizia Ferrari, Varese, IT;

Mara Ferrandi, Milan, IT;

Giuseppe Bianchi, Milan, IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/46 (2006.01); C07D 207/12 (2006.01); C07C 251/58 (2006.01); C07C 279/12 (2006.01); C07C 277/00 (2006.01); C07C 249/04 (2006.01); A61K 31/445 (2006.01); C07C 217/10 (2006.01); C07C 323/25 (2006.01); C07C 281/16 (2006.01); C07C 251/54 (2006.01); C07C 211/31 (2006.01); C07C 251/60 (2006.01);
U.S. Cl.
CPC ...
C07C 251/58 (2013.01); C07C 2103/26 (2013.01); C07C 217/10 (2013.01); C07C 323/25 (2013.01); C07C 277/00 (2013.01); C07C 279/12 (2013.01); C07D 211/46 (2013.01); C07C 281/16 (2013.01); C07D 207/12 (2013.01); C07C 251/54 (2013.01); C07B 2200/07 (2013.01); C07C 249/04 (2013.01); C07C 211/31 (2013.01); C07C 251/60 (2013.01);
Abstract

The present invention relates to new diterpenoid derivatives of formula (I), processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, urinary incontinence, asthma, or Alzheimer's disease and/or to prevent obstructive vascular lesions consequently to arteriotomy and/or angioplasty, and to prevent organ damage in hypertensive patients.


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