The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2014

Filed:

Oct. 26, 2012
Applicant:

Astellas Pharma Inc., Chuo-ku, JP;

Inventors:

Kiyohiro Samizu, Chuo-ku, JP;

Naoyuki Masuda, Chuo-ku, JP;

Kazuhiko Iikubo, Chuo-ku, JP;

Yohei Koganemaru, Chuo-ku, JP;

Noriyuki Kawano, Tsukuba, JP;

Junya Ohmori, Chuo-ku, JP;

Yasuyuki Mitani, Chuo-ku, JP;

Keni Ni, Chuo-ku, JP;

Assignee:

Astellas Pharma Inc., Chuo-ku, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/00 (2006.01); C07D 491/00 (2006.01); C07D 498/00 (2006.01); C07D 513/00 (2006.01); C07D 515/00 (2006.01); C07D 487/00 (2006.01); C07D 221/18 (2006.01); C07D 221/22 (2006.01); C07D 519/00 (2006.01); C07D 471/04 (2006.01); C07D 495/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01); C07D 495/14 (2013.01);
Abstract

[Problem] To provide a compound useful as medicine having PDE4B inhibitory activity, in particular, as an active ingredient of a composition for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like. [Measures for Solution] The present inventors examined compounds having PDE4B inhibitory activity and found that a tricyclic or tetracyclic imidazo[1,2-a]pyridine derivative or salts thereof had a superior PDE4B inhibitory activity, thereby completing the present invention. The imidazo[1,2-a]pyridine derivative can be used as an agent for treating or preventing schizophrenia, Alzheimer's disease, dementia, depression and the like.


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