The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8822678 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 02, 2014

Filed:

Jul. 01, 2013
Applicant:

Tianjin Weijie Technology Co., Ltd., Tianjin, CN;

Inventors:

Honghai Song, Tianjin, CN;

Long Tang, Tianjin, CN;

Wei Chen, Tianjin, CN;

Zheng Li, Tianjin, CN;

Jinzhou Li, Tianjin, CN;

Zhicun Sun, Tianjin, CN;

Jiajin Feng, Tianjin, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/22 (2006.01); C07D 498/18 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07D 498/18 (2013.01); C07F 5/02 (2013.01);
Abstract

A method for synthesizing temsirolimus, the method including: using a substituted boric acid to protect 2,2-dimethylol propionic acid to produce intermediate II; carrying out a reaction between the intermediate II and 2,4,6-trichlorobenzoyl chloride; carrying out condensation reaction between a resulting product and rapamycin to produce intermediate III; and finally using a diol to remove a protecting group from the intermediate III to yield temsirolimus.


Find Patent Forward Citations

Song, Honghai. (2014). Method for synthesizing temsirolimus (U.S. Patent No. 8822678). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8822678

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