The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2014

Filed:

Mar. 08, 2011
Applicants:

Naosuke Maruyama, Joetsu, JP;

Yasuyuki Hirama, Joetsu, JP;

Inventors:

Naosuke Maruyama, Joetsu, JP;

Yasuyuki Hirama, Joetsu, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C08B 11/08 (2006.01); A61K 31/167 (2006.01); A61K 9/00 (2006.01); A61K 47/18 (2006.01); C08B 11/02 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
C08B 11/02 (2013.01); A61K 9/2054 (2013.01); A61K 31/167 (2013.01); A61K 9/0056 (2013.01); A61K 47/18 (2013.01);
Abstract

Provided is nonionic and excellently stable low-substituted hydroxypropylcellulose having improved compressibility and flowability, and further having improved disintegration and texture in oral cavity. More specifically provided is low-substituted hydroxypropylcellulose having a crystallinity of 60% or less, a degree of hydroxypropoxyl substitution of 5 to 9% by weight, and an aspect ratio of less than 2.5, wherein the crystallinity is calculated based on a diffraction intensity by wide-angle X-ray diffraction measurement according to the following formula (1):Crystallinity(%)={()/}×100  (1)wherein Ic means a diffraction intensity at a diffraction angle 2θ of 22.5° and Ia means a diffraction intensity at a diffraction angle 2θ of 18.5°.


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