The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Mar. 27, 2013
Applicant:
Affitech Research As, Oslo, NO;
Inventors:
Lavinia Diana Cicortas Gunnarsson, Oslo, NO;
Didrik Paus, Oslo, NO;
Assignee:
Affitech Research AS, Oslo, NO;
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 1/20 (2006.01); C12N 5/16 (2006.01); C12Q 1/37 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); C07K 16/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2866 (2013.01); C07K 2317/41 (2013.01); C07K 2316/96 (2013.01); C07K 2317/92 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); A61K 45/06 (2013.01); C07K 2317/565 (2013.01); A61K 39/3955 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01);
Abstract
The present invention provides antibodies which bind to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4. Also provided are inter alia immunoconjugates and compositions comprising such antibodies and methods and uses involving such antibodies, particularly in the medical and diagnostic fields.