The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Jul. 20, 2011
Jagabandhu Das, Mercerville, NJ (US);
Soo S. Koo, Hockessin, DE (US);
Anurag S. Srivastava, Belle Mead, NJ (US);
Robert V. Moquin, East Brunswick, NJ (US);
Scott Hunter Watterson, Pennington, NJ (US);
Jagabandhu Das, Mercerville, NJ (US);
Soo S. Koo, Hockessin, DE (US);
Anurag S. Srivastava, Belle Mead, NJ (US);
Robert V. Moquin, East Brunswick, NJ (US);
Scott Hunter Watterson, Pennington, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Disclosed are compounds of Formula (I): (I) or stereoisomers, salts, or prodrugs thereof, wherein: (i) R1 and R2 are independently C-Calkyl, or (ii) Rand Rtogether with the carbon atom to which they are attached, form a cyclic group; and Q is H, Calkyl, phenyl or 5- to 6-membered heteroaryl substituted with zero to 3 substituents, and G is defined herein. Also disclosed are method of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. There compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and chronic inflammatory disease.