The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Jul. 22, 2013
Juan Lorenzo Catena Ruiz, Barcelona, ES;
Carme Serra Comas, Barcelona, ES;
Oscar Rey Puiggros, Barcelona, ES;
Albert Antolin Hernandez, Barcelona, ES;
Ester Monlleo Mas, Barcelona, ES;
Juan Lorenzo Catena Ruiz, Barcelona, ES;
Carme Serra Comas, Barcelona, ES;
Oscar Rey Puiggros, Barcelona, ES;
Albert Antolin Hernandez, Barcelona, ES;
Ester Monlleo Mas, Barcelona, ES;
Laboratorios Salvat, S.A., Esplugues de Llobregat-Barcelona, ES;
Abstract
The compounds of formula (I) are derived from perhydroquinoline and perhydroisoquinoline and are useful as active pharmaceutical ingredients for the prophylaxis or treatment of diseases caused by 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD1) enzyme-associated disorders, such as glaucoma, elevated ocular pressure, metabolic disorders, obesity, metabolic syndrome, dyslipidemia, hypertension, diabetes, atherosclerosis, Cushing's syndrome, psoriasis, rheumatoid arthritis, cognitive disorders, Alzheimer's disease or neurodegeneration.