The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
May. 22, 2006
Sara S. Hadida Ruah, La Jolla, CA (US);
Anna R. Hazlewood, San Diego, CA (US);
Peter D. J. Grootenhuis, San Diego, CA (US);
Ashvani Kumar Singh, San Diego, CA (US);
Thomas Cleveland, San Diego, CA (US);
Frederick F. Van-goor, San Diego, CA (US);
Sara S. Hadida Ruah, La Jolla, CA (US);
Anna R. Hazlewood, San Diego, CA (US);
Peter D. J. Grootenhuis, San Diego, CA (US);
Ashvani Kumar Singh, San Diego, CA (US);
Thomas Cleveland, San Diego, CA (US);
Frederick F. Van-Goor, San Diego, CA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
4-amido-pyrimidine compounds, derivatives and compositions thereof, and synthetic methods described herein are useful for modulating ATP-Binding Cassette ('ABC') transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ('CFTR'). The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.