The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Mar. 28, 2011
Stephen J. Beebe, Norfolk, VA (US);
Karl H. Schoenbach, Norfolk, VA (US);
Richard Heller, Norfolk, VA (US);
Stephen J. Beebe, Norfolk, VA (US);
Karl H. Schoenbach, Norfolk, VA (US);
Richard Heller, Norfolk, VA (US);
Eastern Virginia Medical School, Norfolk, VA (US);
Old Dominion University, Norfolk, VA (US);
Abstract
A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields ('nsPEF's'). The method includes circuitry for delivery of an agent into a cell via known methods followed by the application of nanosecond pulse electric fields to said cell in order to facilitate entry of the agent into the nucleus of the cell. In a preferred embodiment, the present invention is directed to a method of enhancing gene expression in a cell comprising the application of nanosecond pulse electric fields to said cell. An apparatus for generating long and short pulses according to the present invention is also provided. The apparatus includes a pulse generator capable of producing a first pulse having a long duration and low voltage amplitude and a second pulse having a short duration and high voltage amplitude.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile