The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2014

Filed:

Oct. 11, 2006
Applicants:

Andre Levchenko, Ellicott City, MD (US);

Raymond Cheong, Baltimore, MD (US);

Chiaochun J. Wang, Baltimore, MD (US);

Inventors:

Andre Levchenko, Ellicott City, MD (US);

Raymond Cheong, Baltimore, MD (US);

Chiaochun J. Wang, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 1/00 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 15/14 (2006.01);
U.S. Cl.
CPC ...
B01L 3/5025 (2013.01); G01N 15/14 (2013.01); B01L 2300/0816 (2013.01); B01L 2200/06 (2013.01); B01L 2300/0864 (2013.01); B01L 2400/0487 (2013.01); B01L 7/00 (2013.01);
Abstract

Cell stimulation, staining, and visualization are common techniques in both clinical and research settings. The invention is directed to microfluidic devices for in situ cell stimulation, staining, and/or visualization, and related methods for applying one or more stimuli to the cells, and fixing and staining of cells in situ. The device allows for high-throughput screening of living cells using a minimal quantity of reagents where the fate of individual cells can be followed over time.


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