The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Jun. 25, 2004
Applicants:
Brian Anderton, London, GB;
Diane Hanger, London, GB;
Malcolm Ward, Cobham, GB;
Helen Byers, Cobham, GB;
Inventors:
Brian Anderton, London, GB;
Diane Hanger, London, GB;
Malcolm Ward, Cobham, GB;
Helen Byers, Cobham, GB;
Assignee:
Other;
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods for screening for substances capable of modulating the phosphorylation of tau protein are disclosed, and in particular paired helical filament (PHF) tau, and the use of such modulators in the treatment of tauopathies. The assays and screening methods are based on the identification of new phosphorylation sites in PHF tau and new kinases and combinations of kinases as therapeutic targets, in particular the identification of casein kinase 1 as a kinase which phosphorylates tau protein.