The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2014

Filed:

Nov. 24, 2010
Applicants:

Robert E. Johnston, Chapel Hill, NC (US);

Joseph M. Thompson, Raleigh, NC (US);

Inventors:

Robert E. Johnston, Chapel Hill, NC (US);

Joseph M. Thompson, Raleigh, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/193 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); A61K 39/145 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); C12N 2760/16134 (2013.01); A61K 2039/55555 (2013.01); C12N 2770/36132 (2013.01); C12N 2770/36143 (2013.01); A61K 2039/541 (2013.01); A61K 2039/5258 (2013.01); C07K 14/005 (2013.01); A61K 2039/55511 (2013.01); A61K 39/12 (2013.01); A61K 2039/55561 (2013.01); A61K 39/145 (2013.01);
Abstract

The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject.


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