The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2014
Filed:
Jan. 13, 2009
Shankar Kumar, Pleasanton, CA (US);
J. Yun Tso, Menlo Park, CA (US);
Naoya Tsurushita, Palo Alto, CA (US);
Shigeyuki Kon, Sapporo, JP;
Shankar Kumar, Pleasanton, CA (US);
J. Yun Tso, Menlo Park, CA (US);
Naoya Tsurushita, Palo Alto, CA (US);
Shigeyuki Kon, Sapporo, JP;
Gene Techno Science Co., Ltd., Hokkaido, JP;
Kaken Pharmaceutical Co., Tokyo, JP;
Abstract
The present invention provides humanized antibodies that immunospecifically recognize human α9 integrin. Some of these antibodies inhibit the biological functions of the α9 integrin, thereby exhibiting therapeutic effects on various disorders or diseases that are associated with α9 integrin, including cancer, e.g., the growth and metastasis of a cancer cell, and inflammatory diseases, e.g., rheumatoid arthritis, osteoarthritis, hepatitis, bronchial asthma, fibrosis, diabetes, arteriosclerosis, multiple sclerosis, granuloma, an inflammatory bowel disease (ulcerative colitis and Crohn's disease), an autoimmune disease, and so forth.