The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
Feb. 07, 2013
Applicant:
Georgia Health Sciences University Research Institute, Inc., Augusta, GA (US);
Inventors:
Jin-Xiong She, Martinez, GA (US);
Bo Chen, Martinez, GA (US);
Assignee:
Georgia Regents Research Institute, Inc., Augusta, GA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); G01N 33/574 (2006.01); A61K 31/277 (2006.01); A61K 31/12 (2006.01); G01N 33/68 (2006.01); A61K 31/353 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A01K 2267/0362 (2013.01); G01N 33/57407 (2013.01); A61K 31/277 (2013.01); A01K 67/0275 (2013.01); A61K 31/12 (2013.01); G01N 33/57426 (2013.01); G01N 2800/52 (2013.01); A61K 31/353 (2013.01);
Abstract
It has been discovered that STAT5 phosphorylation and CD150 are effective biomarkers for detecting, diagnosing, and monitoring hematological malignancies, including for example lymphomas. Compositions and methods for identifying therapeutic agents for the treatment of hematologic malignancies using p-STAT5, CD150 or both as biomarkers are described.