The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2014

Filed:

Apr. 27, 2011
Applicants:

Kazuhiro Maeda, Osaka, JP;

Jun-ichi Endoh, Osaka, JP;

Akiko Tarao, Osaka, JP;

Kaoru Tashiro, Osaka, JP;

Seigo Ishibuchi, Osaka, JP;

Hidemasa Hikawa, Funabashi, JP;

Inventors:

Kazuhiro Maeda, Osaka, JP;

Jun-ichi Endoh, Osaka, JP;

Akiko Tarao, Osaka, JP;

Kaoru Tashiro, Osaka, JP;

Seigo Ishibuchi, Osaka, JP;

Hidemasa Hikawa, Funabashi, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 251/00 (2006.01); C07D 253/00 (2006.01); C07D 241/02 (2006.01); C07D 403/00 (2006.01); C07D 413/00 (2006.01); C07D 211/68 (2006.01); C07D 401/00 (2006.01); A61K 31/55 (2006.01); A61K 31/497 (2006.01); A61K 31/445 (2006.01); A61K 31/41 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are a novel low-molecular-weight compound that suppresses production of induction type MMPs, particularly MMP-9, rather than production of hemostatic type MMP-2, as well as a prophylactic/therapeutic drug for autoimmune diseases or osteoarthritis. An amide derivative represented by the following formula (I) wherein each symbol is as defined in the specification, or a pharmacologically acceptable salt thereof.


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