The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2014

Filed:

Jun. 02, 2010
Applicants:

Deepak Mohanlal Jain, Surat, IN;

Maneck Khurana, New Delhi, IN;

Hiten Sharadchandra Mehta, Ahmedabad, IN;

Abhay Tatiya, Aurangabad, IN;

Asok Nath, Gurgaon, IN;

Sanjay Mahadeo Gade, Solapur, IN;

Mohan Prasad, Gurgaon, IN;

Subhash Dhar, New Delhi, IN;

Inventors:

Deepak Mohanlal Jain, Surat, IN;

Maneck Khurana, New Delhi, IN;

Hiten Sharadchandra Mehta, Ahmedabad, IN;

Abhay Tatiya, Aurangabad, IN;

Asok Nath, Gurgaon, IN;

Sanjay Mahadeo Gade, Solapur, IN;

Mohan Prasad, Gurgaon, IN;

Subhash Dhar, New Delhi, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a process for preparation of crystalline aprepitant having not more than 15% by weight of Form I content which comprises, a) dissolving aprepitant in a suitable solvent to obtain a solution, b) cooling the solution to 10-15° C., c) optionally seeding the solution with aprepitant Form I crystals, d) adding an anti-solvent to the solution, and e) isolating crystalline aprepitant having not more than 15% by weight of Form I content.


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