The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
Jan. 14, 2011
Yoke-peng Loh, Bethesda, MD (US);
Niamh X. Cawley, Bethesda, MD (US);
Saravana Radha Krishna Murthy, Rockville, MD (US);
Terence K. Lee, Hong Kong, HK;
Yoke-peng Loh, Bethesda, MD (US);
Niamh X. Cawley, Bethesda, MD (US);
Saravana Radha Krishna Murthy, Rockville, MD (US);
Terence K. Lee, Hong Kong, HK;
Abstract
The invention provides a method of determining the prognosis of cancer in a subject. The method comprises (a) obtaining a sample from the subject, (b) analyzing the sample for the expression level of a carboxypeptidase E (CPE) splice variant, and (c) correlating the expression level in the sample with the prognosis of cancer in the subject. The invention further provides a method of diagnosing cancer, methods of treatment, kits for detecting mRNA expression of a CPE-ΔN, and inhibitors of CPE-ΔN and compositions thereof.