The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2014

Filed:

Mar. 18, 2009
Applicants:

Yahua Liu, San Diego, CA (US);

Alexey Vyacheslavovich Anikin, Ivanteevka, RU;

Charles Chamchoumis Mikel, Escondido, CA (US);

Douglas Eric Mcgrath, Carlsbad, CA (US);

Goverdhan Reddy Vavilala, Morrisville, NC (US);

Jason Conrad Pickens, Chula Vista, CA (US);

Aleksander Kadushkin, Zheleznodorozhnyi, RU;

Luyong Jiang, San Marcos, CA (US);

Mohan Santhanam Thiruvazhi, San Diego, CA (US);

Sergey Zozulya, Shrewsbury, MA (US);

Rajendran Vairagoundar, Portage, MI (US);

Tong Zhu, San Diego, CA (US);

Alexander Chucholowski, San Diego, CA (US);

Zheng Yan, San Diego, CA (US);

Alisher Khasanov, Escondido, CA (US);

Christina Gregor, Del Mar, CA (US);

Inventors:

Vlad Edward Gregor, Del Mar, CA (US);

Yahua Liu, San Diego, CA (US);

Alexey Vyacheslavovich Anikin, Ivanteevka, RU;

Charles Chamchoumis Mikel, Escondido, CA (US);

Douglas Eric McGrath, Carlsbad, CA (US);

Goverdhan Reddy Vavilala, Morrisville, NC (US);

Jason Conrad Pickens, Chula Vista, CA (US);

Aleksander Kadushkin, Zheleznodorozhnyi, RU;

Luyong Jiang, San Marcos, CA (US);

Mohan Santhanam Thiruvazhi, San Diego, CA (US);

Sergey Zozulya, Shrewsbury, MA (US);

Rajendran Vairagoundar, Portage, MI (US);

Tong Zhu, San Diego, CA (US);

Alexander Chucholowski, San Diego, CA (US);

Zheng Yan, San Diego, CA (US);

Alisher Khasanov, Escondido, CA (US);

Assignee:

Chembridge Corporation, San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01);
Abstract

Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.


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