The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
Nov. 11, 2009
Myung-hwa Kim, Yongin-si, KR;
Seung-hyun Kim, Seoul, KR;
Sae-kwang Ku, Daegu, KR;
Chun-ho Park, Yongin-si, KR;
Bo-young Joe, Yongin-si, KR;
Kwang-woo Chun, Yongin-si, KR;
In-hae YE, Yongin-si, KR;
Jong-hee Choi, Yongin-si, KR;
Dong-kyu Ryu, Yongin-si, KR;
Ji-seon Park, Yongin-si, KR;
Han-chang Lee, Yongin-si, KR;
Ji-so Choi, Seoul, KR;
Young-chul Kim, Seongnam-si, KR;
Myung-Hwa Kim, Yongin-si, KR;
Seung-Hyun Kim, Seoul, KR;
Sae-Kwang Ku, Daegu, KR;
Chun-Ho Park, Yongin-si, KR;
Bo-Young Joe, Yongin-si, KR;
Kwang-Woo Chun, Yongin-si, KR;
In-Hae Ye, Yongin-si, KR;
Jong-Hee Choi, Yongin-si, KR;
Dong-Kyu Ryu, Yongin-si, KR;
Ji-Seon Park, Yongin-si, KR;
Han-Chang Lee, Yongin-si, KR;
Ji-So Choi, Seoul, KR;
Young-Chul Kim, Seongnam-si, KR;
Je Il Pharmaceutical Co., Ltd., Seoul, KR;
Abstract
The present invention relates to a novel tricyclic derivative with efficient inhibitory activity against poly(ADP-ribose)polymerases (PARP) or pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition containing the same. The tricyclic derivative of the invention is useful for the prevention or treatment of diseases caused by excess PARP activity, especially neuropathic pain, neurodegenerative diseases, cardiovascular diseases, diabetic nephropathy, inflammatory diseases, osteoporosis, and cancer, by inhibiting the activity of poly(ADP-ribose)polymerases.