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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8815813 B1

PDFFull Text
Expired
Date of Patent:
Aug. 26, 2014

Filed:

Jul. 17, 2009

Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome

Applicant:

Neil M. Bodie, Agoura Hills, CA (US);

Inventor:

Neil M. Bodie, Agoura Hills, CA (US);

Assignee:

Trinity Therapeutics, Inc., Agoura Hills, CA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Julie Ha

Int. Cl.
CPC ...
A61K 38/10 (2006.01); C07K 7/08 (2006.01); C07K 7/00 (2006.01); C07K 16/10 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); C07K 7/08 (2013.01); C07K 7/00 (2013.01); C07K 16/1081 (2013.01);
Abstract

Polypeptides and other compounds that can bind specifically to the C2-C3 cleft of an immunoglobulin molecule, as well as methods for using such polypeptides and compounds to inhibit Fc-mediated immune complex formation in viral infection, are described. For example, polypeptides and other compounds can be used to inhibit binding of DF-associated, immune-complexed IgG anti-DF viron(s) or DV viral antigens to FγR, ADE of DF/DHF/DSS infections by inhibition of DF viral antigen binding to immune complexed IgG, FγR and immune complexed IgG mC1q (membrane C1q) or soluble C1q binding.

Find Patent Forward Citations

Bodie, Neil. (2014). Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome (U.S. Patent No. 8815813). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8815813

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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