The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2014

Filed:

Jul. 01, 2010
Applicants:

Ki-dong Park, Seoul, KR;

Yoon-ki Joung, Incheon, KR;

Kyung-min Park, Seoul, KR;

Inventors:

Ki-Dong Park, Seoul, KR;

Yoon-Ki Joung, Incheon, KR;

Kyung-Min Park, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61K 45/00 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); C07K 14/495 (2006.01); C07K 14/50 (2006.01); C07K 14/485 (2006.01); A61L 27/54 (2006.01); A61K 9/00 (2006.01); A61L 27/52 (2006.01); A61K 47/42 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2300/41 (2013.01); A61K 9/0024 (2013.01); A61L 2300/602 (2013.01); A61L 2400/06 (2013.01); A61L 2300/416 (2013.01); A61L 2300/43 (2013.01); A61L 2300/414 (2013.01); A61L 2300/252 (2013.01); A61L 2300/256 (2013.01); A61K 47/42 (2013.01); A61L 2300/406 (2013.01);
Abstract

Disclosed are in situ-forming injectable hydrogel and medical uses thereof. In the in situ-forming injectable hydrogel two or more homogeneous or heterogeneous polymers are bonded to each other by a dehydrogenation reaction between phenol or aniline moieties on adjacent polymers, wherein a polymer backbone is grafted with a phenol or aniline moiety using a linker. In contrast to conventional hydrogel, the in situ-forming injectable hydrogel is superior in terms of in vivo stability and mechanical strength thanks to the introduction of a water-soluble polymer as a linker which leads to an improvement in the reactivity of phenol or aniline moieties. Having the advantage of superior bio stability and mechanical strength, the hydrogel finds a variety of applications in the biomedical field.


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