The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2014

Filed:

Dec. 04, 2008
Applicants:

Padma Malyala, Santa Clara, CA (US);

Derek O'hagan, Winchester, MA (US);

Manmohan Singh, Lexington, MA (US);

Inventors:

Padma Malyala, Santa Clara, CA (US);

Derek O'Hagan, Winchester, MA (US);

Manmohan Singh, Lexington, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01); A61K 31/437 (2006.01); A61K 9/16 (2006.01); A61K 39/07 (2006.01); A61K 31/4745 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 9/1647 (2013.01); A61K 2039/57 (2013.01); A61K 2039/55511 (2013.01); A61K 39/07 (2013.01); A61K 31/4745 (2013.01); A61K 39/39 (2013.01);
Abstract

The invention provides, inter alia, immunogenic compositions that comprise (a) a first antigen, (b) at least first and second adjuvants, wherein the first adjuvant comprises microparticles and wherein the second adjuvant comprises an imidazoquinoline compound, and (c) a pharmaceutically acceptable excipient, which compositions elicits an immune response when administered to a vertebrate subject. The invention also provides methods of producing immunogenic compositions and methods for using immunogenic compositions (e.g., for treatment), among other benefits.


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