The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
May. 27, 2010
Applicant:
Alex J. Harvey, Athens, GA (US);
Inventor:
Alex J. Harvey, Athens, GA (US);
Assignee:
Synageva BioPharma Corp., Lexington, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/02 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); A01K 67/027 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8509 (2013.01); A01K 2267/01 (2013.01); C07K 2317/41 (2013.01); A01K 2217/052 (2013.01); A01K 67/0275 (2013.01); C07K 16/2887 (2013.01); C07K 2317/732 (2013.01); A01K 2267/02 (2013.01); A01K 2227/30 (2013.01); C07K 2317/23 (2013.01); C07K 2317/734 (2013.01); C07K 2317/24 (2013.01); Y10S 424/80 (2013.01); Y10S 424/801 (2013.01); Y10S 530/867 (2013.01);
Abstract
The invention is drawn to a composition comprising an isolated mixture of cytotoxic anti-CD20 antibody molecules produced in a transgenic avian. The antibody molecules have a heavy chain and a light chain whose amino acid sequences set forth in SEQ ID NOs: 4 and 5 and exhibit an increased level of cytotoxicity as compared to anti-CD20 antibody molecules produced in CHO cells.