The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
Dec. 05, 2008
Applicants:
K. Dane Wittrup, Chestnut Hill, MA (US);
Jeffrey Ravetch, New York, NY (US);
Stephen Lael Sazinsky, Brookline, MA (US);
Inventors:
K. Dane Wittrup, Chestnut Hill, MA (US);
Jeffrey Ravetch, New York, NY (US);
Stephen Lael Sazinsky, Brookline, MA (US);
Assignees:
Massachusetts Institute of Technology, Cambridge, MA (US);
The Rockefeller University, New York, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is based, in part, on our discovery of immunoglobulins (e.g., immunoglobulin G (IgG)) polypeptides (e.g., murine or human IgG, such as human IgG1) that are aglycosylated yet retain the ability to bind to an Fc receptor, such as an activating Fc receptor (e.g., FcγRIIA and/or FcγRIIIA).