The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2014
Filed:
Jun. 17, 2013
Applicant:
Virginia Tech Intellectual Properties, Inc., Blacksburg, VA (US);
Inventors:
Rafael V. Davalos, Blacksburg, VA (US);
Marissa N. Rylander, Blacksburg, VA (US);
Christopher B. Arena, Burlington, NC (US);
Yong Woo Lee, Blacksburg, VA (US);
Assignee:
Virginia Tech Intellectual Properties, Inc., Blacksburg, VA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 18/18 (2006.01); A61N 1/32 (2006.01); C12N 13/00 (2006.01); A61N 1/05 (2006.01);
U.S. Cl.
CPC ...
A61N 1/327 (2013.01); A61N 1/05 (2013.01); C12N 13/00 (2013.01);
Abstract
The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.