The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Mar. 05, 2009
Applicants:

Shipeng Yu, Exton, PA (US);

Glenn Fung, Madison, WI (US);

Steven Florian Petit, Maastricht, NL;

Hugo J. W. L. Aerts, Maastricht, NL;

Claudia Offermann, Kerkrade, NL;

Michel Oellers, Sint Joost, NL;

Philippe Lambin, Genappe-Bousval, BE;

Dirk DE Ruysscher, Tervuren, BE;

Andreas Lubbertus Aloysius Johannes Dekker, Maastricht, NL;

Sriram Krishnan, Exton, PA (US);

Inventors:

Shipeng Yu, Exton, PA (US);

Glenn Fung, Madison, WI (US);

Steven Florian Petit, Maastricht, NL;

Hugo J. W. L. Aerts, Maastricht, NL;

Claudia Offermann, Kerkrade, NL;

Michel Oellers, Sint Joost, NL;

Philippe Lambin, Genappe-Bousval, BE;

Dirk de Ruysscher, Tervuren, BE;

Andreas Lubbertus Aloysius Johannes Dekker, Maastricht, NL;

Sriram Krishnan, Exton, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G01N 31/00 (2006.01); G06G 7/48 (2006.01); G06G 7/58 (2006.01); A61N 5/10 (2006.01); G06F 19/00 (2011.01); G06N 99/00 (2010.01); G06T 11/00 (2006.01);
U.S. Cl.
CPC ...
A61N 5/1031 (2013.01); G06F 19/3437 (2013.01); G06N 99/005 (2013.01); G06T 11/00 (2013.01);
Abstract

Functional imaging information is used to determine a probability of residual disease given a treatment. The functional imaging information shows different characteristic levels for different regions of the tumor. The probability is output for planning use and/or used to automatically determine dose by region. Using the probability, the dose may be distributed by region so that some regions receive a greater dose than other regions. This distribution by region of dose more likely treats the tumor with a same dose, allows a lesser dose to sufficient treat the tumor, and/or allows a greater dose with a lesser or no increase in risk to normal tissue. The dose plan may account for personalized tumors as each patient may have distinct tumors. Probability of dose application accuracy may also be used, so that a combined treatment probability allows efficient dose planning.


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