The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Jan. 07, 2010
Applicants:

Martha E. Rodriguez, Boudler, CO (US);

David A. Mareska, Boulder, CO (US);

Jeremy J. Hans, Saint Louis, MO (US);

Darren M. Harvey, Boulder, CO (US);

Robert D. Groneberg, Boulder, CO (US);

Michael O'sullivan, Denver, CO (US);

Inventors:

Martha E. Rodriguez, Boudler, CO (US);

David A. Mareska, Boulder, CO (US);

Jeremy J. Hans, Saint Louis, MO (US);

Darren M. Harvey, Boulder, CO (US);

Robert D. Groneberg, Boulder, CO (US);

Michael O'Sullivan, Denver, CO (US);

Assignee:

Array BioPharma Inc., Boulder, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/00 (2006.01); C07D 403/14 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for preventing and/or treating a metabolic disease, cerebrovascular disease, etc. which comprises administering to a mammal an effective amount of the compound of the formula (I): wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof. And a novel compound of the formula (I-1): wherein all symbols have the same meanings as defined in the specification; a salt thereof, an N-oxide thereof, a solvate thereof, or a prodrug thereof has an anti-diabetic effect and a neuroprotective effect. Accordingly, the compound of the formula (I) and the compound of the formula (I-1) are useful in a method for preventing and/or treating for a metabolic disease such as diabetes, cerebrovascular disease such as stroke, etc.


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