The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Sep. 20, 2007
Applicants:

Christina Yamada, Boulder, CO (US);

Anastasia Khvorova, Boulder, CO (US);

Rob Kaiser, Broomfield, CO (US);

Emily Anderson, Lafayette, CO (US);

Devin Leake, Denver, CO (US);

Inventors:

Christina Yamada, Boulder, CO (US);

Anastasia Khvorova, Boulder, CO (US);

Rob Kaiser, Broomfield, CO (US);

Emily Anderson, Lafayette, CO (US);

Devin Leake, Denver, CO (US);

Assignee:

GE Healthcare Dharmacon, Inc., Lafayette, CO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/11 (2013.01);
Abstract

Provided herein are tripartite oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene. The tripartite oligonucleotide complexes of the disclosure may include a conjugate moiety that facilitates delivery to a cell, tissue or organism without the aid of a transfection reagent.


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