The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Apr. 28, 2009
Applicants:

Lars Lannfelt, Stockholm, SE;

Joakim Bergström, Uppsala, SE;

Martin Ingelsson, Uppsala, SE;

Pär Gellerfors, Lindingö, SE;

Inventors:

Lars Lannfelt, Stockholm, SE;

Joakim Bergström, Uppsala, SE;

Martin Ingelsson, Uppsala, SE;

Pär Gellerfors, Lindingö, SE;

Assignee:

BioArctic Neuroscience AB, Stockholm, SE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); G01N 33/567 (2006.01); A61K 38/17 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); A61K 38/1709 (2013.01); C07K 16/18 (2013.01); G01N 2333/4709 (2013.01); Y10S 530/839 (2013.01);
Abstract

A vaccine for delaying an onset of or for treatment of an α-synuclein-related disorder in an individual comprises a therapeutically effective amount of isolated stabilized soluble α-synuclein oligomer having a lower formation rate to a non-soluble aggregated form than a non-stabilized oligomer of the α-synuclein. An antibody for delaying an onset of or for treatment of an α-synuclein-related disorder in an individual binds soluble α-synuclein. Methods for delaying an onset of for treatment or for prevention of an α-synuclein-related disorder employ the vaccine or antibody. Methods of detecting α-synuclein oligomers employ the antibody.


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