The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Nov. 17, 2005
Applicants:

Lawrence W. Bergman, Lansdale, PA (US);

Akhil B. Vaidya, Wynnewood, PA (US);

Inventors:

Lawrence W. Bergman, Lansdale, PA (US);

Akhil B. Vaidya, Wynnewood, PA (US);

Assignee:

Drexel University, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 1/00 (2006.01); A61K 39/015 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Isolated proteins and nucleic acid sequence encoding such protein that interacts with a red blood cell to be invaded by a malaria parasite and link with a component of the actin-myosin based machinery of the malaria parasite are provided. In addition methods for identifying agents which inhibit the function of these proteins as chemotherapeutic and/or immunologic agents for treatment and prevention of malaria infections are provided. Compositions for treatment and prevention of malaria infections and methods for preventing and treating malaria infections are also provided.


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