The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Sep. 23, 2011
Applicants:

Nicholas J. Donato, Ann Arbor, MI (US);

Christiane Wobus, Dexter, MI (US);

Hollis D. Showalter, Ann Arbor, MI (US);

Moshe Talpaz, Ann Arbor, MI (US);

Jeffrey W. Perry, Ypsilanti, MI (US);

Roderick J. Sorenson, Ann Arbor, MI (US);

Mary X. O'riordan, Ann Arbor, MI (US);

Yafei Jin, Ann Arbor, MI (US);

Inventors:

Nicholas J. Donato, Ann Arbor, MI (US);

Christiane Wobus, Dexter, MI (US);

Hollis D. Showalter, Ann Arbor, MI (US);

Moshe Talpaz, Ann Arbor, MI (US);

Jeffrey W. Perry, Ypsilanti, MI (US);

Roderick J. Sorenson, Ann Arbor, MI (US);

Mary X. O'Riordan, Ann Arbor, MI (US);

Yafei Jin, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/444 (2006.01); A61K 31/4433 (2006.01); A61K 31/4436 (2006.01); A61K 31/4439 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed herein are methods of inhibiting a deubiquitinase (DUB), methods of treating pathogenic infections (e.g., viral, bacterial, and/or parasitic), methods of inhibiting cell proliferation, methods of treating a neurodegenerative disease, methods of treating one or more symptoms of a neurodegenerative disease or a genetic disorder, and compounds, wherein the compound can have a structure of formula (III):


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