The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Apr. 01, 2011
Applicants:

Rajinder Singh, Belmont, CA (US);

Dane Goff, Redwood City, CA (US);

Jiaxin Yu, San Carlos, CA (US);

Sacha Holland, San Francisco, CA (US);

Thilo J. Heckrodt, San Francisco, CA (US);

Pingyu Ding, Foster City, CA (US);

Joane Litvak, Oakland, CA (US);

Jing Zhang, Foster City, CA (US);

Inventors:

Rajinder Singh, Belmont, CA (US);

Dane Goff, Redwood City, CA (US);

Jiaxin Yu, San Carlos, CA (US);

Sacha Holland, San Francisco, CA (US);

Thilo J. Heckrodt, San Francisco, CA (US);

Pingyu Ding, Foster City, CA (US);

Joane Litvak, Oakland, CA (US);

Jing Zhang, Foster City, CA (US);

Assignee:

Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/4375 (2006.01); A61K 31/4196 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 471/08 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/4375 (2013.01); A61K 31/4196 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 471/08 (2013.01); C07D 405/14 (2013.01);
Abstract

Polycyclic aryl and polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl catalytic activity are also disclosed.


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