The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2014
Filed:
Aug. 23, 2012
Ashley Sue Mccarron, Bedford, NH (US);
Todd B. Sells, Southborough, MA (US);
Matthew Stirling, Randolph, MA (US);
Stephen G. Stroud, Medford, MA (US);
Ashley Sue McCarron, Bedford, NH (US);
Todd B. Sells, Southborough, MA (US);
Matthew Stirling, Randolph, MA (US);
Stephen G. Stroud, Medford, MA (US);
Millennium Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
Disclosed are chemical entities which are inhibitors of Nedd8-activating enzyme (NAE), namely, the compound {(1S,2S,4R)-4-[(6-{[(1R,2S)-5-chloro-2-methoxy-2,3-dihydro-1H-inden-1-yl]amino}pyrimidin-4-yl)oxy]-2-hydroxycyclopentyl}methyl sulfamate and pharmaceutically acceptable salts thereof; solid state forms thereof; and prodrugs thereof. Also disclosed are methods of using the chemical entities to treat disorders such as cancer.